Is Vitamin D2 Really Bioequivalent to Vitamin D3?
نویسندگان
چکیده
منابع مشابه
Vitamin D2 versus D3 – Scientific Evidences
Vitamins D3 and D2 are chemically different. In contrast to vitamin D3, vitamin D2 has a double bond between carbons 22 and 23 and a methyl group on carbon 24 in its side chain. Irrespective of their chemical differences, the human body uses the same enzymatic pathways to transform these vitamins to their pro-hormone (conditional vitamins) and hormone forms. There are ongoing debates in the lit...
متن کاملVitamin D2 is much less effective than vitamin D3 in humans.
Vitamins D(2) and D(3) are generally considered to be equivalent in humans. Nevertheless, physicians commonly report equivocal responses to seemingly large doses of the only high-dose calciferol (vitamin D(2)) available in the U.S. market. The relative potencies of vitamins D(2) and D(3) were evaluated by administering single doses of 50,000 IU of the respective calciferols to 20 healthy male v...
متن کاملVitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D.
CONTEXT Two reports suggested that vitamin D2 is less effective than vitamin D3 in maintaining vitamin D status. OBJECTIVE Our objective was to determine whether vitamin D2 was less effective than vitamin D3 in maintaining serum 25-hydroxyvitamin D levels or increased the catabolism of 25-hydroxyvitamin D3. SUBJECTS AND DESIGN This was a randomized, placebo-controlled, double-blinded study ...
متن کاملEvidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2.
In all species tested, except humans, biological differences between vitamins D2 and D3 are accepted as fact. To test the presumption of equivalence in humans, we compared the ability of equal molar quantities of vitamin D2 or D3 to increase serum 25-hydroxyvitamin D [25(OH)D], the measure of vitamin D nutrition. Subjects took 260 nmol (approximately 4000 IU) vitamin D2 (n=17) or vitamin D3 (n=...
متن کاملSCHOOL OF MEDICINE Thesis EVALUATION OF THE BIOAVAILABILITY AND METABOLISM OF VITAMIN D2 IN A MUSHROOM SUPPLEMENT COMPARED TO SUPPLEMENTAL VITAMIN D2 AND SUPPLEMENTAL VITAMIN D3 by JAIMEE
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2016
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2016-1528